Xylazine (Rompun) is an α2 class of adrenergic receptor agonist. Xylazine is a clonidine analoque that acts on presynaptic and postsynaptic receptors of the central and peripheral nervous systems as an a 2-adrenergic agonist.
Store at -20°C
white to off-white powder
DMSO ：44 mg/mL (199.7 mM)
Xylazine can be used for sedation, anesthesia, muscle relaxation, and analgesia in animals such as horses, cattle and other non-human mammals. Xylazine has recently emerged as a recreational drug, especially in Puerto Rico. Administration of xylazine (0.17 mg/kg of body weight, diluted to a 10-ml volume, using 0.9% NaCl) induced approximately 2.5 hours of local analgesia without apparent side effects. Higher doses of xylazine caused mild hind limb ataxia. Administration of lidocaine-induced a similar duration of analgesia, with severe hind limb ataxia (100% incidence) .
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